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Greg Isenberg1h 8m

9 biggest startup ideas right now (AI, B2C, mobile etc)

TL;DR

  • Live, messy, human content is becoming more valuable as AI sanitizes everything — Jonathan points to Twitch, TVPN’s $100M+ sale, and his own Tuesday streams reaching 1,000-2,000 people to argue that unscripted business content can support €400K-€500K businesses through events, merch, and memberships.

  • “Action apps” are a huge mobile opportunity because AI can do tasks instead of just showing interfaces — Greg’s thesis is that the next wave after mobile-first is agent-first, with examples like email apps that automatically handle 80% of messages instead of making users triage inboxes manually.

  • Loneliness is both a real social crisis and a business category with recurring-revenue potential — They cite the stat that roughly 22% of Americans have no close friends, then highlight businesses like 222 and Fabric that turn matching, events, and community spaces into paid memberships.

  • Older users are massively underserved despite having money, time, and clear pain points — Greg frames “elder tech” around the 70M+ boomers in the U.S., while Jonathan adds that Facilitator’s best customers are often 45+ and still respond well to channels like Facebook ads.

  • The most practical AI business right now may be selling ‘junior employees,’ not replacing senior talent — Their shared idea is to verticalize AI workers around specific job titles and jobs-to-be-done, like YouTube production workflows, and sell them as clear labor-saving systems rather than vague automation.

  • The winning move is often to marry a niche, not a product — Jonathan describes how the same creative retreat that might make $5K in a general market made $110K for entrepreneurs, and Greg sums it up with: “date the product, marry the niche.”

The Breakdown

A Twitch-style business show sold for over $100 million, and Greg Isenberg and Jonathan Courtney argue that’s just one sign of where the real startup opportunities are heading: live human content, AI agents that actually do work, and niche communities people will gladly pay for. Their strongest theme is simple but sharp: stop building for generic users, pick underserved audiences with money and pain, and stack media, community, and products around them.

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